CORRELATION OF CIGARETTE SMOKING WITH SYSTEMIC BLOOD PRESSURE, SERUM CHOLESTEROL AND BILIRUBIN LEVELS

Abstract

Objective: Correlation of cigarette smoking and cigarette smoke pack years with systemic blood pressure, serum cholesterol and serum bilirubin. Study Design: Cross sectional study Place & Duration: Indus Medical College, Tando Muhammad Khan from June 2016 to October 2017. Subjects & Methods: A sample of 100 smokers (cases) and 100 non- smokers (control) were selected for study protocol. Sample was selected according to criteria. Cases and control were age and body weight matched. Systemic blood pressure, serum bilirubin and cholesterol levels were estimated in cases and control and results were analysed and compared statistically by SPSS (ver 22.0) at 95% confidence interval. Results: Smokers showed total mean ± SD pack years of 4.77 ± 2.87. Duration and cigarettes smoked were noted as 3.95 ± 0.56 years and 20.5 ± 5.56 respectively. Smokers showed statistically high systolic and diastolic blood pressure and serum cholesterol compared to control (P =0.0001). Serum bilirubin was found low in cases compared to control (P =0.0001). Cigarette pack years showed positive correlation with systolic BP, diastolic BP and serum cholesterol but negative correlation with serum bilirubin. Conclusion: Smoking is a risk factor for high systemic blood pressure and serum cholesterol and showed positive correlation.