FREQUENCY OF VITAMIN D DEFICIENCY IN HEALTHY ADULT POPULATION - A CROSS SECTIONAL STUDY

Abstract

Objective: To determine vitamin D, serum calcium and phosphate levels in adults. Study Design: Cross sectional study Study setting & Duration: Outpatient Department, Indus Medical College Hospital Tando Muhammad Khan from May 2017 to October 2017. Subjects and Methods: A sample of 100 volunteer participants (49 male and 51 female) was selected according to pre defined criteria. Venous blood samples were collected under aseptic conditions. Serum calcium and phosphate were estimated by standard laboratory procedures. Vitamin D was measured by ARCHITECT I 1000 system. Data was analyzed on SPSS (ver 22.0). Results: Serum calcium, serum phosphate and vitamin D in male and female were noted as 9.21±0.68 and 8.62±0.46 mg/dl (P=0.0001), 3.98±1.02 and 3.39±1.01 mg/dl (P=0.0004) & 28.82±8.71 and 21.73 ± 4.6 ng/dl (P=0.0001) respectively. Mean± SD vitamin D sufficiency, insufficiency and deficiency were noted as 36.65±6.15, 24.60 ±2.35 and 16.52±1.71 ng/ml respectively (P=0.0001). 23% study subjects reveals sufficient vitamin D levels, while insufficiency and deficiency was noted in 77% of subjects (P=0.0001). Conclusion: The present study reports a frequency of 77% vitamin D insufficiency and deficiency in aged healthy adults.